PMM2 Protein (AA 1-246) (His tag)
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- Target See all PMM2 Proteins
- PMM2 (Phosphomannomutase 2 (PMM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-246
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PMM2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PMM2, 1-246aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS – PAGE
- Top Product
- Discover our top product PMM2 Protein
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Phosphomannomutase 2 (PMM2) (AA 1-246) protein (GST tag)
PMM2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Phosphomannomutase 2 (PMM2) (AA 47-111) protein (GST tag)PMM2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Phosphomannomutase 2 (PMM2) (AA 1-242) protein (Strep Tag)Crystallography grade PMM2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Phosphomannomutase 2 (PMM2) (AA 2-246) protein (His tag)Crystallography grade PMM2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Phosphomannomutase 2 (PMM2) protein (Myc-DYKDDDDK Tag)PMM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
- Storage
- 4 °C
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- Target
- PMM2 (Phosphomannomutase 2 (PMM2))
- Alternative Name
- PMM2 (PMM2 Products)
- Synonyms
- cb626 Protein, zgc:56149 Protein, MGC82869 Protein, pmm2 Protein, CDG1 Protein, CDG1a Protein, CDGS Protein, PMI Protein, PMI1 Protein, PMM 2 Protein, AI585868 Protein, C86848 Protein, phosphomannomutase 2 Protein, phosphomannomutase 2 S homeolog Protein, pmm2 Protein, PMM2 Protein, pmm2.S Protein, PTRG_02815 Protein, Tsp_00480 Protein, Pmm2 Protein
- Background
- PMM2, also known as Phosphomannomutase 2, belongs to the eukaryotic PMM family. PMM2 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. It catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mutations in PMM2 are associated with Congenital disorders of glycosylation (CDG)-Ia, an autosomal recessive disorder characterized by central nervous system dysfunction and multiorgan failure. Recombinant human PMM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CDG1, CDG1a, CDGS, Phosphomannomutase 2. NCBI no.: NP_000294
- Molecular Weight
- 30.2 kDa (266aa), confirmed by MALDI-TOF
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