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MSRB1 Protein (AA 1-116) (His tag)

SEPX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667227
  • Target See all MSRB1 (SEPX1) Proteins
    MSRB1 (SEPX1) (Selenoprotein X, 1 (SEPX1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-116
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MSRB1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    SEPX1, 1-116aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SEPX1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1 mM DTT, 0.1 mM PMSF, 2mM EDTA, 10% Glycerol
    Storage
    4 °C
  • Target
    MSRB1 (SEPX1) (Selenoprotein X, 1 (SEPX1))
    Alternative Name
    SEPX1 (SEPX1 Products)
    Synonyms
    MsrB Protein, MsrB1-A Protein, SePR Protein, SelX-A Protein, cb687 Protein, selx Protein, sepx1 Protein, sepx1a Protein, wu:fa03e09 Protein, SEPX1 Protein, SELR Protein, SELX Protein, SepR Protein, D17Wsu82e Protein, SelR Protein, Sepr Protein, Sepx1 Protein, selX Protein, MSRB1 Protein, DKFZp469G2418 Protein, methionine sulfoxide reductase B1a Protein, methionine sulfoxide reductase B1 Protein, selenoprotein X, 1 Protein, msrb1a Protein, MSRB1 Protein, msrb1 Protein, Sepx1 Protein, Msrb1 Protein
    Background
    SEPX1, also known as Methionine sulfoxide reductase B1 (MSRB1), is a selenoprotein. Methionine sulfoxide reductases(MSRs) catalyze reduction of free and protein-bound methionine sulfoxides to corresponding methionines. The oxidation of methionine by ROS generates a diastereomeric mixture of methionine-S-sulfoxide (Met-S-SO) and methionine-R-sulfoxide (Met-R-SO). Two distinct enzyme families evolved for reduction of these sulfoxides, with methionine-S-sulfoxide reductase (MsrA) being stereospecific for Met-S-SO and methionine-R-sulfoxide reductase (MsrB) for Met-R-SO. In bacteria, the selenocystein (Sec/U) element is located immediately following the UGA codon within the reading frame for the selenoprotein so we mutated Sec-95 to Cys. Recombinant human SEPX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Selenoprotein X, HSPC270, MSRB1, SELR, SELX, MSRB1, Methionine-R-sulfoxide reductase B1, U95C. NCBI no.: NP_057416
    Molecular Weight
    14.8 kDa(136aa), confirmed by MALDI-TOF
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