SH2D1A Protein (AA 1-128) (His tag)
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- Target See all SH2D1A Proteins
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-128
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SH2D1A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SH2D1A, 1-128aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product SH2D1A Protein
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SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (His tag)
SH2D1A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
SH2 Domain Containing 1A (SH2D1A) (AA 1-128) protein (GST tag)SH2D1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
SH2 Domain Containing 1A (SH2D1A) (AA 1-126) protein (Strep Tag)Crystallography grade SH2D1A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
SH2 Domain Containing 1A (SH2D1A) proteinSH2D1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
SH2 Domain Containing 1A (SH2D1A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SH2D1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 7.5) containing 1 mM DTT, 10% Glycerol
- Storage
- 4 °C
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- Target
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- Alternative Name
- SH2D1A (SH2D1A Products)
- Synonyms
- DSHP Protein, EBVS Protein, IMD5 Protein, LYP Protein, MTCP1 Protein, SAP Protein, SAP/SH2D1A Protein, XLP Protein, XLPD Protein, RGD1562408 Protein, Gm686 Protein, SH2D1A Protein, SH2 domain containing 1A Protein, SH2D1A Protein, Sh2d1a Protein
- Background
- SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD. NCBI no.: NP_002342
- Molecular Weight
- 16.3 kDa(148aa), confirmed by MALDI-TOF
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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