HUS1 Protein (AA 1-280) (His tag)
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- Target See all HUS1 Proteins
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-280
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HUS1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HUS1, 1-280aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HUS1 Protein
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HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) protein (His tag)
HUS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) protein (GST tag)HUS1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) protein (Strep Tag)Crystallography grade HUS1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 1-280) protein (Strep Tag)Crystallography grade HUS1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
HUS1 Checkpoint Homolog (S. Pombe) (HUS1) (AA 2-280), (partial) protein (His-SUMO Tag)HUS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
HUS1 Checkpoint Homolog (S. Pombe) (HUS1) protein (Myc-DYKDDDDK Tag)HUS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 40% Glycerol
- Storage
- 4 °C
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- Target
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
- Alternative Name
- HUS1 (HUS1 Products)
- Synonyms
- hHUS1 Protein, mHus1 Protein, XHus1 Protein, hus1 Protein, HUS1 checkpoint clamp component Protein, checkpoint clamp complex protein Hus1 Protein, HUS1 checkpoint clamp component L homeolog Protein, HUS1 Protein, Hus1 Protein, hus1 Protein, hus1.L Protein
- Background
- HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. This protein associates with Rad9 and Rad1 to form the 9-1-1(RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response. Recombinant human HUS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: checkpoint protein HUS1,. NCBI no.: NP_004498
- Molecular Weight
- 33.8 kDa (300aa), confirmed by MALDI-TOF
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