MAPRE1 Protein (AA 1-268) (His tag)

Catalog No. ABIN667310

Product Details

Target: MAPRE1 (Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1))

Protein Type: Recombinant

Protein Characteristics: AA 1-268

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MAPRE1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: MAPRE1, 1-268aa, Human, His tag, E.coli

Purity: > 90 % by SDS – PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 2mM DTT, 0.1M NaCl.

Storage: 4 °C

Target Details

Target: MAPRE1 (Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1))

Alternative Name: MAPRE1 (MAPRE1 Products)

Synonyms: EB1 Protein, 5530600P05Rik Protein, AI462499 Protein, AI504412 Protein, AW260097 Protein, BIM1p Protein, D2Ertd459e Protein, Eb1 Protein, MAPRE1 Protein, mapre1l Protein, wu:fi33c06 Protein, zgc:55428 Protein, zgc:77807 Protein, mapre1 Protein, wu:fa01e12 Protein, wu:fc23e11 Protein, zgc:85755 Protein, MGC52508 Protein, eb1 Protein, xEB1B Protein, Mapre3 Protein, microtubule associated protein RP/EB family member 1 Protein, microtubule-associated protein, RP/EB family, member 1 Protein, microtubule-associated protein, RP/EB family, member 1a Protein, microtubule-associated protein, RP/EB family, member 1b Protein, microtubule associated protein RP/EB family member 1 L homeolog Protein, microtubule associated protein RP/EB family member 1 S homeolog Protein, MAPRE1 Protein, Mapre1 Protein, mapre1a Protein, mapre1b Protein, mapre1.L Protein, mapre1.S Protein

Background: MAPRE1, also known as EB1, belongs to the intermediate/early gene family. This protein first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. It localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. MAPRE1 is involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. Recombinant human MAPRE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Microtubule-associated protein RP/EB family member 1. , EB1, MGC117374, MGC129946. NCBI no.: NP_036457

Molecular Weight: 32.2 kDa (288aa) confirmed by MALDI-TOF

Pathways: M Phase