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TDO2 Protein (AA 1-406) (His tag)

TDO2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667369
  • Target See all TDO2 Proteins
    TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-406
    Origin
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TDO2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    TDO2, 1-406aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TDO2 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
    Storage
    4 °C
  • Target
    TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))
    Alternative Name
    TDO2 (TDO2 Products)
    Synonyms
    Tdo2 Protein, tdo2l Protein, fi30d08 Protein, zgc:63488 Protein, wu:fi30d08 Protein, TDO2 Protein, fb62b10 Protein, tdo2 Protein, wu:fb62b10 Protein, zgc:103693 Protein, DDBDRAFT_0190495 Protein, DDBDRAFT_0231363 Protein, DDB_0190495 Protein, DDB_0231363 Protein, TDO Protein, TO Protein, TPH2 Protein, TRPO Protein, AA407491 Protein, chky Protein, Tdo Protein, tryptophan 2,3-dioxygenase b Protein, tryptophan 2,3-dioxygenase Protein, tryptophan 2,3-dioxygenase a Protein, tryptophan 2,3-dioxygenase L homeolog Protein, tdo2b Protein, tdo2 Protein, TDO2 Protein, MADE_02822 Protein, CtCNB1_3657 Protein, tdo2a Protein, CNC04830 Protein, tdo Protein, Mrub_2119 Protein, Deipr_2235 Protein, Acav_1166 Protein, Mesop_4278 Protein, Tdo2 Protein, tdo2.L Protein
    Background
    TDO2, also known as TDO, is a ferrous heme enzyme that catalyzes the first and rate-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. It incorporates oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. Recombinant human TDO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Tryptophan 2,3-dioxygenase, TDO, TPH2, TRPO. NCBI no.: NP_005642
    Molecular Weight
    50.0 kDa (426aa), confirmed by MALDI-TOF
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