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AKR1D1 Protein (AA 1-326) (His tag)

AKR1D1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667380
  • Target See all AKR1D1 Proteins
    AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-326
    Origin
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This AKR1D1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    AKR1D1, 1-326aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product AKR1D1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 100mM NaCl
    Storage
    4 °C
  • Target
    AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
    Alternative Name
    AKR1D1 (AKR1D1 Products)
    Synonyms
    3o5bred Protein, CBAS2 Protein, SRD5B1 Protein, 3-oxo-5-beta-steroid 4-dehydrogenase-like Protein, aldo-keto reductase family 1 member D1 Protein, aldo-keto reductase family 1, member D1 Protein, aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) Protein, LOC491379 Protein, AKR1D1 Protein, Akr1d1 Protein
    Background
    Aldo-keto reductase family 1, member D1, also known as AKR1D1, is a member of the AKR superfamily. The AKR family of proteins are soluble NADPH oxidoreductases. They play important roles in the metabolism of drugs, carcinogens and reactive aldehydes. AKR1D1 is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones which carry a delta (4)-3-one structure. AKR1D1 is highly expressed in liver, colon and testis. Deficiency of this enzyme may contribute to hepatic dysfunction. Recombinant human AKR1D1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Aldo-keto reductase family 1, member D1, 3o5bred, CBAS2, SRD5B1. NCBI no.: NP_005980
    Molecular Weight
    39.5 kDa (346aa) confirmed by MALDI-TOF
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
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