CLCF1 Protein (AA 28-225) (His tag)
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- Target See all CLCF1 Proteins
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-225
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CLCF1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CLCF1, 28-225aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
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Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 29-225) protein (GST tag)
CLCF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-225) protein (His tag)Crystallography grade CLCF1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 28-225) protein (His tag)Crystallography grade CLCF1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (Transcript Variant 1) (Active) proteinCLCF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM sodium citrate (pH 3.5), 0.4M Urea, 10% glycerol
- Storage
- 4 °C
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- Target
- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
- Alternative Name
- CLCF1 (CLCF1 Products)
- Synonyms
- clc Protein, nr6 Protein, bsf3 Protein, nnt1 Protein, ciss2 Protein, CLCF1 Protein, BSF-3 Protein, BSF3 Protein, CISS2 Protein, CLC Protein, NNT-1 Protein, NNT1 Protein, NR6 Protein, Bsf3 Protein, Clc Protein, cardiotrophin like cytokine factor 1 Protein, cardiotrophin-like cytokine factor 1 Protein, clcf1 Protein, CLCF1 Protein, Clcf1 Protein
- Background
- CLCF1, also known as cardiotrophin-like cytokine factor 1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225-amino acids with a 27-aa signal peptide, a molecular mass of 22 kDa in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Synonyms: Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6. NCBI no.: NP_037378
- Molecular Weight
- 24.6 kDa (219aa)
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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