Glutathione Reductase Protein (GSR) (AA 43-522) (His tag)

Catalog No. ABIN667622

Product Details

Target: Glutathione Reductase (GSR)

Protein Type: Recombinant

Protein Characteristics: AA 43-522

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Glutathione Reductase protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: GSR, 43-522aa, Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Storage: 4 °C

Target Details

Target: Glutathione Reductase (GSR)

Alternative Name: GSR (GSR Products)

Synonyms: GR Protein, ATGR2 Protein, EMB2360 Protein, glutathione reductase Protein, AI325518 Protein, D8Ertd238e Protein, Gr-1 Protein, Gr1 Protein, DDBDRAFT_0168952 Protein, DDBDRAFT_0231410 Protein, DDB_0168952 Protein, DDB_0231410 Protein, 2151 Protein, CG2151 Protein, DTR Protein, Dm-TrxR Protein, DmTR Protein, DmTrx Protein, DmTrxR Protein, DmTrxR-1 Protein, Dmel\\CG2151 Protein, Gr Protein, Trx Protein, TrxR Protein, TrxR-1 Protein, Trxr1 Protein, anon-WO03040301.185 Protein, anon-WO03040301.187 Protein, dTrxR Protein, dmtrxr-1 Protein, gr Protein, l(1)G0154 Protein, l(1)G0379 Protein, l(1)G0477 Protein, l(1)G0481 Protein, trxr-1 Protein, gor1 Protein, glutathione reductase, gro-2 Protein, glutathione reductase Protein, glutathione-disulfide reductase Protein, GR; GRase Protein, mitochondrial glutathione reductase Pgr1 Protein, Glutathione reductase (GR) (GRase) Protein, Thioredoxin reductase-1 Protein, glutathione-disulfide reductase family protein Protein, glutathione reductase 1 Protein, GR Protein, gor Protein, GSR Protein, GSR1 Protein, Gsr_2 Protein, Gsr Protein, GSHR1 Protein, gsr Protein, LbGR Protein, pgr1 Protein, GSHR2 Protein, GLR2 Protein, Bcen_2392 Protein, RPE_1989 Protein, HCAG_02219 Protein, SJAG_01162 Protein, Trxr-1 Protein, PF14_0192 Protein, POPTR_0001s14480g Protein, gsr1 Protein

Background: Glutathione reductase, also known as GSR, is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein and plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+ ->2GSH + NADP+. In most eukaryotic cells, GSR maintains the ratio of [GSH] / [GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis. Recombinant human GSR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Glutathione reductase, GLUR, GRD1. NCBI no.: NP_000628

Molecular Weight: 54.3 kDa (504aa) confirmed by MALDI-TOF

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis