CHMP4A Protein (AA 1-265) (His tag)
-
- Target See all CHMP4A Proteins
- CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-265
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CHMP4A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CHMP4A, 1-265aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CHMP4A Protein
-
Charged Multivesicular Body Protein 4A (CHMP4A) (AA 1-265) protein (His tag)
CHMP4A Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Charged Multivesicular Body Protein 4A (CHMP4A) (AA 1-222) protein (Strep Tag)Crystallography grade CHMP4A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Charged Multivesicular Body Protein 4A (CHMP4A) protein (Myc-DYKDDDDK Tag)CHMP4A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl, 0.1mM PMSF, 1mM EDTA
- Storage
- 4 °C
-
- Target
- CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))
- Alternative Name
- CHMP4A (CHMP4A Products)
- Synonyms
- C14orf123 Protein, CHMP4 Protein, CHMP4B Protein, HSPC134 Protein, SHAX2 Protein, SNF7 Protein, SNF7-1 Protein, VPS32-1 Protein, VPS32A Protein, charged multivesicular body protein 4A Protein, CHMP4A Protein
- Background
- CHMP4A (Chromatin-modifying protein 4a) belongs to the SNF7 family and functions as chromatin-modifying proteins. It probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. Also during HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins via the association of CHMP4 and a protein recruited by HIV-1 p6, which is present in viral Gag assembly and budding. CHMP4A expressed at higher level in heart, kidney, liver and skeletal muscle. Recombinant human CHMP4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: chromatin modifying protein 4A, CHMP4, CHMP4B, HSPC134, SHAX2, SNF7, SNF7-1, VPS32-1, VPS32A. NCBI no.: NP_054888
- Molecular Weight
- 32.0kDa (285aa), confirmed by MALDI-TOF
-
