TICAM2 Protein (AA 1-235) (His tag)
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- Target See all TICAM2 Proteins
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-235
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TICAM2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TICAM2, 1-235aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TICAM2 Protein
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Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) protein (His tag)
TICAM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 1-235) protein (GST tag)TICAM2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 2-235) protein (His tag)Crystallography grade TICAM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (AA 2-232) protein (His tag)Crystallography grade TICAM2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Toll-Like Receptor Adaptor Molecule 2 (TICAM2) protein (Myc-DYKDDDDK Tag)TICAM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
- Alternative Name
- TICAM2 (TICAM2 Products)
- Synonyms
- MyD88-4 Protein, TICAM-2 Protein, TIRAP3 Protein, TIRP Protein, TRAM Protein, B430113A10 Protein, Tirp Protein, Trif Protein, toll like receptor adaptor molecule 2 Protein, toll-like receptor adaptor molecule 2 Protein, TICAM2 Protein, Ticam2 Protein
- Background
- Toll TIR domain-containing adapter molecule 2, also known as TICAM2, is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TICAM-2, a cytoplasmic protein, physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TLR4 signaling to TICAM-1, which in turn activates IRF-3. It is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Recombinant human TICAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TIR domain-containing adapter molecule 2, TICAM-2, TIRAP3, TIRP, TRAM. NCBI no.: NP_067681
- Molecular Weight
- 29.4 kDa (259aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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