PGAM2 Protein (AA 1-253) (His tag)

Catalog No. ABIN667687

Product Details

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Protein Type: Recombinant

Protein Characteristics: AA 1-253

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PGAM2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: PGAM2, 1-253aa , Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Storage: 4 °C

Target Details

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Alternative Name: PGAM2 (PGAM2 Products)

Synonyms: zgc:63876 Protein, GSD10 Protein, PGAM-M Protein, PGAMM Protein, D14Mgh1 Protein, Pgmut Protein, phosphoglycerate mutase 2 Protein, phosphoglycerate mutase 2 (muscle) Protein, phosphoglycerate mutase 2 L homeolog Protein, Pgam2 Protein, PGAM2 Protein, pgam2 Protein, pgam2.L Protein

Background: PGAM2, also known as phosphoglycerate mutase 2, belongs to the phosphoglycerate mutase family. Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. Recombinant human PGAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: GSD10, PGAM-M, PGAMM. NCBI no.: NP_000281

Molecular Weight: 30.9 kDa (273aa) confirmed by MALDI-TOF