DTNBP1 Protein (AA 1-270) (His tag)
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- Target See all DTNBP1 Proteins
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-270
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DTNBP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Dysbindin, 1-270aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DTNBP1 Protein
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Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-100) protein (GST tag)
DTNBP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-351) protein (GST tag)DTNBP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-351) protein (His tag)Crystallography grade DTNBP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-352) protein (His tag)Crystallography grade DTNBP1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Dystrobrevin Binding Protein 1 (DTNBP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DTNBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Dystrobrevin Binding Protein 1 (DTNBP1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DTNBP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- In 20 mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 0.5mM DTT, 20% glycerol
- Storage
- 4 °C
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- Target
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
- Alternative Name
- Dysbindin (DTNBP1 Products)
- Background
- Dysbindin is a ubiquitously expressed protein that binds to alpha- and beta-dystrobrevins, components of the dystrophin-associated protein complex (DPC) in both muscle and nonmuscle cells. Dysbindin has been strongly implicated in schizophrenia (SZ) susceptibility by a series of independent genetic association and gene expression studies. Among its known functions, dysbindin is part of a protein complex, termed the biogenesis of lysosome-related organelles complex 1 (BLOC-1), the molecular components of which might be involved in the regulation of vesicular trafficking and dendrite branching. Dysbindin effects for brain volume and cortical thickness appear driven by different neurobiological processes. Recombinant human Dysbindin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: DTNBP1, DBND, HPS7, SDY, Dystrobrevin-binding protein 1 isoform C Dystrobrevin binding protein 1, Hermansky Pudlak syndrome 7 protein. NCBI no.: NP_898862
- Molecular Weight
- 34.6 kDa (307aa), confirmed by MALDI-TOF.
- Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
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