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FADD Protein (AA 1-208) (His tag)

FADD Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667749
  • Target See all FADD Proteins
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-208
    Origin
    • 7
    • 3
    Human
    Source
    • 7
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This FADD protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    FADD, 1-208 aa, Human, His-tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product FADD Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
    Storage
    4 °C
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Alternative Name
    FADD (FADD Products)
    Synonyms
    MORT1 Protein, Mort1/FADD Protein, Mort1 Protein, TNFRSF6 Protein, adaptor Protein, fadd Protein, mort1 Protein, xfadd Protein, Fas associated via death domain Protein, Fas (TNFRSF6)-associated via death domain Protein, Fas associated via death domain S homeolog Protein, Fas (tnfrsf6)-associated via death domain Protein, FADD Protein, Fadd Protein, fadd.S Protein, fadd Protein
    Background
    FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules. Recombinant FADD protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GIG3, MORT1, Fas-associated via death domain, Fas-associated death domain FADD protein, Fas associated via death domain, Fas (TNFRSF6) associated via death domain, Fas associating death domain containing protein, Fas associating protein with death domain, Fas TNFRSF6 associated via death domain, Fas associating protein, GIG 3, MGC8528, Growth inhibiting gene 3 protein, MORT 1, H sapiens mRNA for mediator of receptor induced toxicity, Mediator of receptor induced toxicity,. NCBI no.: NP_003815
    Molecular Weight
    27.4 kDa (244aa), confirmed by MALDI-TOF.
    Pathways
    Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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