BAG3 Protein (AA 1-575) (His tag)
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- Target See all BAG3 Proteins
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-575
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BAG3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- BAG3, 1-575aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product BAG3 Protein
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BCL2-Associated Athanogene 3 (BAG3) (AA 1-575) protein (GST tag)
BAG3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Associated Athanogene 3 (BAG3) (AA 2-575) protein (His tag)Crystallography grade BAG3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
BCL2-Associated Athanogene 3 (BAG3) (AA 2-577) protein (His tag)Crystallography grade BAG3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
BCL2-Associated Athanogene 3 (BAG3) (AA 2-577) protein (His tag)BAG3 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
BCL2-Associated Athanogene 3 (BAG3) (AA 2-577) protein (His-SUMO Tag)BAG3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
BCL2-Associated Athanogene 3 (BAG3) protein (Myc-DYKDDDDK Tag)BAG3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM EDTA, 0.1mM PMSF, 10% glycerol
- Storage
- 4 °C
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- Target
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Alternative Name
- BAG3 (BAG3 Products)
- Synonyms
- bag3-A Protein, MGC53113 Protein, zgc:100859 Protein, BAG3 Protein, ATBAG3 Protein, BCL-2-associated athanogene 3 Protein, T28J14.160 Protein, T28J14_160 Protein, BAG-3 Protein, BIS Protein, CAIR-1 Protein, MFM6 Protein, AA407278 Protein, Bis Protein, mg638 Protein, BCL2 associated athanogene 3 L homeolog Protein, BCL2-associated athanogene 3 Protein, BCL2 associated athanogene 3 Protein, BCL-2-associated athanogene 3 Protein, Bcl2-associated athanogene 3 Protein, bag3.L Protein, bag3 Protein, BAG3 Protein, Bag3 Protein
- Background
- BAG3 was reported initially as a protein-refolding cochaperone of the bcl2 binding protein BAG family and as upregulated in response to persistent stress of cellular calcium balance dysregulation. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Also, it has been shown to diminish stress-induced apoptosis. Recombinant human BAG3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: BIS, CAIR-1, BAG family molecular chaperone regulator 3 BAG 3, Bcl 2 binding protein, BCL2 associated athanogene 3, BCL2 binding athanogene 3, Docking protein CAIR 1. NCBI no.: NP_004272
- Molecular Weight
- 63.7 kDa (595aa)
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