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Calreticulin Protein (CALR) (AA 18-417) (His tag)

CALR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN667783
  • Target See all Calreticulin (CALR) Proteins
    Calreticulin (CALR)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-417
    Origin
    • 11
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 14
    • 11
    • 3
    • 3
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Calreticulin protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    Calreticulin, 18-417aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product CALR Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M Nacl, 10% glycerol
    Storage
    4 °C
  • Target
    Calreticulin (CALR)
    Alternative Name
    Calreticulin (CALR Products)
    Synonyms
    CRT Protein, RO Protein, SSA Protein, cC1qR Protein, crc Protein, crt Protein, Calregulin Protein, CG9429 Protein, Clr Protein, Dmel\\CG9429 Protein, anon-EST:Liang-2.11 Protein, anon-EST:Liang-2.17 Protein, anon-EST:fe3D7 Protein, clone 2.11 Protein, clone 2.17 Protein, eth Protein, potp Protein, cc1qr Protein, ssa Protein, NV19007 Protein, CRP55 Protein, ERp60 Protein, HACBP Protein, CHOT1 Protein, CHT1 Protein, CT1 Protein, AA589632 Protein, CRTR Protein, Creat Protein, CCDS1 Protein, calrl2 Protein, fc66d10 Protein, wu:fc66d10 Protein, wu:fj50c03 Protein, zgc:66153 Protein, calreticulin Protein, calreticulin L homeolog Protein, Calreticulin Protein, putative calreticulin Protein, solute carrier family 6 member 8 Protein, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Protein, CALR Protein, calr.L Protein, Crt Protein, crt Protein, CRT Protein, Calr Protein, calr Protein, LMJF_31_2600 Protein, Crc Protein, Slc6a8 Protein, SLC6A8 Protein, LOC8269812 Protein
    Background
    Calreticulin is the major calcium binding protein found in smooth muscle sarcoplasmic reticulum (SR) and non-muscle endoplasmic reticulum (ER) membranes. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, Calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. Recombinant human Calreticulin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: cC1qR, CRT, FLJ26680, RO, SSA, Autoantigen RO, CALR, CALR protein, Calregulin, Calreticulin, CRP55, CRTC, ERp60, FLJ26680, grp60, HACBP, Sicca syndrome antigen A. NCBI no.: NP_004334
    Molecular Weight
    48.7 kDa (421aa), confirmed by MALDI-TOF
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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