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RAP1A Protein (AA 1-181) (His tag)

RAP1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN667792
  • Target See all RAP1A Proteins
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-181
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RAP1A protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    RAP1A, 1-181aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product RAP1A Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 5mM DTT, 200mM NaCl
    Storage
    4 °C
  • Target
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    Alternative Name
    RAP1A (RAP1A Products)
    Synonyms
    KREV-1 Protein, KREV1 Protein, RAP1 Protein, SMGP21 Protein, AI848598 Protein, G-22K Protein, Krev-1 Protein, Rap1 Protein, RAP-1A Protein, rap 1A Protein, wu:fc66g06 Protein, zgc:86676 Protein, krev-1 Protein, krev1 Protein, rap1 Protein, RAP1A, member of RAS oncogene family Protein, RAS-related protein 1a Protein, RAP1A, member of RAS oncogene family a Protein, RAP1A, member of RAS oncogene family L homeolog Protein, RAP1A Protein, Rap1a Protein, rap1aa Protein, rap1a.L Protein
    Background
    Ras-related protein Rap-1A (RAP1A) belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. This Protein Induces morphological reversion of a cell line transformed by a Ras oncogene and Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Recombinant human RAP1A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: KREV1, G-22K, C21KG, Ras-related protein Rap-1A, G 22K, GTP binding protein smg p21A, KREV 1, OTTHUMP00000013741, RAP 1A, RAP1, RAP1A member of RAS oncogene family , Ras related protein Krev 1, Ras related protein Rap 1A, RAS related protein RAP1A, SMGP21. NCBI no.: NP_001010935
    Molecular Weight
    22.8kDa (201aa) confirmed by MALDI-TOF
    Pathways
    TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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