Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) (AA 1-167) protein (His tag)

Details for Product No. ABIN667818, Supplier: Log in to see
Protein Name
  • wu:fc05f09
  • wu:fi84b06
  • zgc:101724
  • MGC53390
  • MGC80084
  • MGC132077
  • PTP4A2
  • ptp4a2
  • Prl-2
  • HH13
  • HH7-2
  • HU-PP-1
  • OV-1
  • PRL-2
  • PRL2
  • PTP4A
  • PTPCAAX2
  • ptp-IV1a
  • ptp-IV1b
  • protein tyrosine phosphatase type IVA, member 2b
  • protein tyrosine phosphatase 4a2
  • protein tyrosine phosphatase type IVA, member 2
  • protein tyrosine phosphatase type IVA, member 2 L homeolog
  • ptp4a2b
  • ptp4a2
  • PTP4A2
  • ptp4a2.L
  • Ptp4a2
Protein Characteristics
AA 1-167
5
3
1
1
1
1
1
1
Origin
Human
12
1
1
Source
Escherichia coli (E. coli)
8
2
2
1
1
Protein Type
Recombinant
Purification tag / Conjugate
His tag
Application
SDS-PAGE (SDS)
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Characteristics PTP4A2, 1-167aa, Human, His tag, E.coli
Purity > 90 % by SDS - PAGE
Background Protein tyrosine phosphatase type IVA 2 isoform 1, also known as PTP4A2, belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTP4A2 is localized to the early endosome that play regulatory roles in a variety of cellular processes. This protein was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Recombinant human PTP4A2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Protein tyrosine phosphatase type IVA 2 isoform 1, HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, ptp-IV1b, PTP4A, PTPCAAX2, EC 3.1.3.48 , HH13 , HH7 2 , HUPP 1 , HUPP1 , OV 1 , OV1 , PRL 2 , PRL2 , Protein tyrosine phosphatase 4a2 , Protein tyrosine phosphatase of regenerating liver 2 , Protein tyrosine phosphatase type IVA member 2 isoform 1 , PTP (CAAXII) , ptp IV1a , ptp IV1b , PTP4A , PTPCAAX2 ,. NCBI no.: NP_536316
Molecular Weight 23.2 kDa (203aa), confirmed by MALDI-TOF
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml (determined by Bradford assay)
Buffer Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Storage 4 °C
Supplier Images
SDS-PAGE (SDS) image for Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) (AA 1-167) protein (His tag) (ABIN667818) Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2) (AA 1-167) protein (His tag)
Background publications Werner, Lee, DeCamp, Crowell, Randall, Crowell: "Enhanced cell cycle progression and down regulation of p21(Cip1/Waf1) by PRL tyrosine phosphatases." in: Cancer letters, Vol. 202, Issue 2, pp. 201-11, 2003 (PubMed).

Si, Zeng, Ng, Hong, Pallen: "Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32875-82, 2001 (PubMed).

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