PFDN6 Protein (AA 1-129) (His tag)
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- Target See all PFDN6 Proteins
- PFDN6 (Prefoldin Subunit 6 (PFDN6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-129
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PFDN6 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PFDN6, 1-129aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PFDN6 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by BCA assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- PFDN6 (Prefoldin Subunit 6 (PFDN6))
- Alternative Name
- PFDN6 (PFDN6 Products)
- Synonyms
- hke2 Protein, ke-2 Protein, pfd6 Protein, h2-ke2 Protein, pfdn6a Protein, 23.m05913 Protein, H-2Ke2 Protein, Ke-2 Protein, Pfdn6 Protein, H2-KE2 Protein, HKE2 Protein, KE-2 Protein, PFD6 Protein, zgc:66282 Protein, pfdn6 Protein, pfdn6b Protein, Ke2 Protein, prefoldin subunit 6 S homeolog Protein, prefoldin subunit 6 (predicted) Protein, prefoldin subunit 6 Protein, prefoldin subunit 6 L homeolog Protein, pfdn6.S Protein, SPAC3A11.13 Protein, BBOV_IV004800 Protein, AOR_1_2254174 Protein, CMU_042830 Protein, pfdn6 Protein, Pfdn6 Protein, PFDN6 Protein, pfdn6.L Protein
- Background
- PFDN6, also known as HKE2 or PFD6, is a subunit of the heteromeric prefoldin complex that chaperones nascent actin and alpha- and beta-tubulin chains pending their transfer to the cytosolic chaperonin containing TCP1 (CCT) complex. It binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it and binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Recombinant human PFDN6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Prefoldin subunit 6, H2-KE2, HKE2, KE-2, MGC70744, PFD6. NCBI no.: NP¬_055075
- Molecular Weight
- 16.7 kDa (149aa) confirmed by MALDI-TOF
- Pathways
- Unfolded Protein Response
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