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HSD17B8 Protein (AA 1-261) (His tag)

HSD17B8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN667899
  • Target See all HSD17B8 Proteins
    HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-261
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 10
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This HSD17B8 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    HSD17B8, 1-261aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HSD17B8 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 150mM NaCl
    Storage
    4 °C
  • Target
    HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))
    Alternative Name
    HSD17B8 (HSD17B8 Products)
    Synonyms
    KE6 Protein, fabgl Protein, zgc:112550 Protein, si:dz12f11.4 Protein, HKE6 Protein, FABGL Protein, ke6 Protein, fabg Protein, hke6 Protein, ring2 Protein, h2-ke6 Protein, d6s2245e Protein, D17H6S112E Protein, H-2Ke6 Protein, Hsd17b8 Protein, Ke-6 Protein, Ke6 Protein, Ring2 Protein, D6S2245E Protein, FABG Protein, H2-KE6 Protein, RING2 Protein, SDR30C1 Protein, dJ1033B10.9 Protein, Fabgl Protein, hydroxysteroid (17-beta) dehydrogenase 8 Protein, hydroxysteroid 17-beta dehydrogenase 8 Protein, H2-K region expressed gene 6 Protein, hsd17b8 Protein, HSD17B8 Protein, H2-Ke6 Protein, Hsd17b8 Protein
    Background
    HSD17B8, also known as estradiol 17-beta-dehydrogenase 8, belongs to the short-chain dehydrogenases/reductases (SDR) family. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. It may play a role in biosynthesis of fatty acids in mitochondria. Recombinant human HSD17B8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Estradiol 17-beta-dehydrogenase 8, FABGL, HKE6, RING2. NCBI no.: NP_055049
    Molecular Weight
    29.1 kDa (281aa), confirmed by MALDI-TOF
    Pathways
    Steroid Hormone Biosynthesis
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