CTDSP1 Protein (AA 1-260) (His tag)
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- Target See all CTDSP1 Proteins
- CTDSP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-260
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CTDSP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CTDSP1, 1-260aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CTDSP1 Protein
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CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) (AA 1-260) protein (His tag)
CTDSP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) (AA 1-260) protein (GST tag)CTDSP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) (AA 1-261) protein (Strep Tag)Crystallography grade CTDSP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) (AA 1-261) protein (Strep Tag)Crystallography grade CTDSP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CTDSP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CTDSP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- CTDSP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1))
- Alternative Name
- CTDSP1 (CTDSP1 Products)
- Synonyms
- CTDSP1 Protein, NIF3 Protein, NLI-IF Protein, NLIIF Protein, SCP1 Protein, fj83f12 Protein, im:7141428 Protein, wu:fj83f12 Protein, zgc:113169 Protein, GIP Protein, Nif3 Protein, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 Protein, CTD small phosphatase 1 Protein, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Protein, CTDSP1 Protein, Ctdsp1 Protein, ctdsp1 Protein, HCAG_04820 Protein, CTRG_06220 Protein
- Background
- Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, also known as CTDSP1, is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Also it negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recombinant human CTDSP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, NLIIF, SCP1, NIF3. NCBI no.: NP_872580
- Molecular Weight
- 31.2 kDa (280aa), confirmed by MALDI-TOF
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