SPSB1 Protein (AA 24-233) (His tag)

Catalog No. ABIN667909

Product Details

Target: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Protein Type: Recombinant

Protein Characteristics: AA 24-233

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SPSB1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: SPSB1, 24-233aa, Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay )

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl

Storage: 4 °C

Target Details

Target: SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))

Alternative Name: SPSB1 (SPSB1 Products)

Synonyms: SSB-1 Protein, SSB1 Protein, 1110014L01Rik Protein, 4930422J18Rik Protein, AI596360 Protein, AI854583 Protein, splA/ryanodine receptor domain and SOCS box containing 1 Protein, SPSB1 Protein, Spsb1 Protein

Background: SPRY domain-containing SOCS box protein 1 (SPSB1), also known as SSB1, is a member of the SOCS box protein subfamily. This protein contains a central SPRY domain and a C-terminal SOCS box. Although some of the SOCS protein subfamilies function as adaptors for a large family of ubiquitin-protein isopeptide ligases to regulate certain signaling pathways, the function of the SSB subfamily remains to be determined. SPSB1 may play an important role in enhancing the HGF-induced Erk-Elk-1-SRE pathway. Over expression of SPSB1 exhibited no effect on the basal level or epidermal growth factor-induced SRE-luciferase activity. Recombinant human SPSB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: SPRY domain-containing SOCS box protein 1, SSB-1, SSB1. NCBI no.: NP_079382

Molecular Weight: 26.1 kDa (231aa) confirmed by MALDI-TOF