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AFT1 Protein (AA 1-271) (His tag)

AFT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN668009
  • Target See all AFT1 Proteins
    AFT1 (Activating Transcription Factor 1 (AFT1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-271
    Origin
    • 6
    • 2
    • 2
    Human
    Source
    • 6
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This AFT1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    ATF1, 1-271aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product AFT1 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 0.2M NaCl, 2mM EDTA
    Storage
    4 °C
  • Target
    AFT1 (Activating Transcription Factor 1 (AFT1))
    Alternative Name
    ATF1 (AFT1 Products)
    Synonyms
    ews-atf1 Protein, fus/atf-1 Protein, treb36 Protein, ATF1 Protein, EWS-ATF1 Protein, FUS/ATF-1 Protein, TREB36 Protein, Atf-1 Protein, wu:fc92c07 Protein, zgc:64099 Protein, activating transcription factor 1 Protein, activating transcription factor 1 L homeolog Protein, atf1 Protein, ATF1 Protein, MGC85066 Protein, atf1.L Protein, Atf1 Protein
    Background
    Activating transcription factor 1, also known as ATF1, is a cyclic-AMP dependent transcription factor. ATF1 is expressed in a wide variety of cell types and is capable of dimerizing with CREB. MSK1 and MSK2 protein kinases are required for the stress-induced phosphorylation of transcription factors CREB and ATF1 in primary embryonic fibroblasts. Epidermal growth factor induction of c-jun expression requires ATF1 and MEF2 sites in the c-jun promoter. Recombinant human ATF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Activating transcription factor 1, EWS-ATF1, FUS/ATF-1, TREB36. NCBI no.: NP_005162
    Molecular Weight
    31.8 kDa (295aa) confirmed by MALDI-TOF
    Pathways
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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