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TIFA Protein (AA 1-184) (His tag)

TIFA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN668024
  • Target See all TIFA Proteins
    TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-184
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TIFA protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    TIFA, 1-184aa , Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TIFA Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))
    Alternative Name
    TIFA (TIFA Products)
    Synonyms
    TIFA Protein, xtifa Protein, T2BP Protein, T6BP Protein, TIFAA Protein, T2bp Protein, Ab2-389 Protein, TRAF interacting protein with forkhead associated domain Protein, TRAF-interacting protein with forkhead-associated domain Protein, TRAF-interacting protein with forkhead-associated domain S homeolog Protein, TIFA Protein, tifa Protein, Tifa Protein, tifa.S Protein
    Background
    TIFA, also known as TRAF-interacting protein with FHA domain-containing protein A, is an adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. This protein induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. Recombinant human TIFA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: TRAF-interacting protein with FHA domain-containing protein A, T2BP, T6BP, TIFAA. NCBI no.: NP_443096
    Molecular Weight
    24.0 kDa (208aa) confirmed by MALDI-TOF
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