CFP Protein (AA 28-469) (His tag)

Catalog No. ABIN6809911

Product Details

Target: CFP (Complement Factor P (CFP))

Protein Type: Recombinant

Protein Characteristics: AA 28-469

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CFP protein is labelled with His tag.

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: CFP (Complement Factor P (CFP))

Alternative Name: Properdin (CFP Products)

Synonyms: BFD Protein, PFC Protein, PFD Protein, PROPERDIN Protein, BCFG Protein, Pfc Protein, Properdin Protein, complement factor properdin Protein, CFP Protein, Cfp Protein

Background: Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

Molecular Weight: 50.7 kDa

NCBI Accession: NP_001138724

Pathways: Complement System