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SIGLEC15 Protein (AA 20-263) (Fc Tag)

SIGLEC15 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN6923189
  • Target See all SIGLEC15 Proteins
    SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 20-263
    Origin
    • 16
    • 8
    • 5
    Cynomolgus
    Source
    • 21
    • 6
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This SIGLEC15 protein is labelled with Fc Tag.
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SIGLEC15 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
    Storage
    -20 °C
  • Target
    SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
    Alternative Name
    Siglec-15 (SIGLEC15 Products)
    Synonyms
    RGD1565948 Protein, CD33L3 Protein, HsT1361 Protein, SIGLEC-15 Protein, Cd33l3 Protein, EG620235 Protein, SIGLEC-I Protein, sialic acid binding Ig-like lectin 15 Protein, sialic acid binding Ig like lectin 15 Protein, Siglec15 Protein, SIGLEC15 Protein
    Background
    Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
    Molecular Weight
    52.7 kDa
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