PVRL4 Protein (AA 32-349) (His tag)

Catalog No. ABIN6950975

Product Details

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Protein Type: Recombinant

Protein Characteristics: AA 32-349

Origin: Cynomolgus

Source: HEK-293 Cells

Purification tag / Conjugate: This PVRL4 protein is labelled with His tag.

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Alternative Name: Nectin-4 (PVRL4 Products)

Synonyms: PVRL4 Protein, si:ch211-155e24.1 Protein, 1200017F15Rik Protein, Prr4 Protein, RGD1559826 Protein, EDSS1 Protein, LNIR Protein, PRR4 Protein, nectin-4 Protein, nectin cell adhesion molecule 4 Protein, NECTIN4 Protein, nectin4 Protein, Nectin4 Protein

Background: Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50 % , 49 % and 86 %o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

Molecular Weight: 36.0 kDa

NCBI Accession: XP_005541277

Pathways: Cell-Cell Junction Organization