CLEC12A Protein (AA 65-265) (His tag)
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- Target See all CLEC12A Proteins
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 65-265
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC12A protein is labelled with His tag.
- Sequence
- AA 65-265
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CLEC12A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
- Alternative Name
- CLEC12A (CLEC12A Products)
- Synonyms
- MGC179455 Protein, CLL-1 Protein, CLL1 Protein, DCAL-2 Protein, MICL Protein, D230024O04 Protein, KLRL1 Protein, Micl Protein, C-type lectin domain family 12 member A Protein, C-type lectin domain family 12, member a Protein, C-type lectin domain family 12, member A Protein, CLEC12A Protein, Clec12a Protein
- Background
- CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
- Molecular Weight
- 25.6 kDa
- NCBI Accession
- NP_612210
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