IL3RA Protein (AA 19-305) (Fc-His Tag)
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- Target See all IL3RA Proteins
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-305
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL3RA protein is labelled with Fc-His Tag.
- Application
- ELISA
- Purpose
- Recombinant human CD123 protein with C-terminal human Fc and 6xHis tag
- Specificity
- CD123 (Thr19-Arg305) hFc (Glu99-Ala330) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IL3RA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Alternative Name
- CD123 (IL3RA Products)
- Background
- Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor a chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells
- Molecular Weight
- predicted molecular mass of 80-90 kDa after removal of the signal peptide.
- Gene ID
- 3563
- UniProt
- P26951
- Pathways
- JAK-STAT Signaling
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