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Poliovirus Receptor Protein (PVR) (mFc-His Tag)

PVR Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Catalog No. ABIN6961100
  • Target See all Poliovirus Receptor (PVR) Proteins
    Poliovirus Receptor (PVR)
    Protein Type
    Recombinant
    Origin
    • 25
    • 9
    • 3
    • 2
    • 1
    Human
    Source
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Poliovirus Receptor protein is labelled with mFc-His Tag.
    Application
    ELISA
    Purpose
    Recombinant human CD155 protein with C-terminal mouse Fc and 6xHis tag
    Specificity
    CD155 (Trp21-Asn343) mFc (Pro99-Lys330) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product PVR Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -20 °C,-80 °C
    Expiry Date
    12 months
  • Target
    Poliovirus Receptor (PVR)
    Alternative Name
    CD155 (PVR Products)
    Synonyms
    PVR Protein, CD155 Protein, HVED Protein, NECL5 Protein, Necl-5 Protein, PVS Protein, TAGE4 Protein, 3830421F03Rik Protein, D7Ertd458e Protein, Taa1 Protein, Tage4 Protein, mE4 Protein, necl-5 Protein, poliovirus receptor Protein, PVR Protein, Pvr Protein
    Background
    Synonymes: PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5
    Description: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    predicted molecular mass of 62.2 kDa after removal of the signal peptide. The apparent molecular mass of CD155-mFc-His is 95-130 kDa due to glycosylation.
    Gene ID
    5817
    UniProt
    P15151
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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