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FAP Protein (AA 26-761) (mFc Tag)

This Recombinant FAP protein is produced in HEK-293 Cells.
Catalog No. ABIN6964119

Quick Overview for FAP Protein (AA 26-761) (mFc Tag) (ABIN6964119)

Target

See all FAP Proteins
FAP (Fibroblast Activation Protein, alpha (FAP))

Protein Type

Recombinant

Origin

  • 21
  • 7
  • 3
  • 3
Mouse

Source

  • 19
  • 7
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Protein Characteristics

    AA 26-761

    Purification tag / Conjugate

    This FAP protein is labelled with mFc Tag.

    Purpose

    Recombinant mouse FAP protein with C-terminal mFc tag

    Specificity

    Mouse FAP (Leu26-Asp761) mFc (Pro99-Lys330)

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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    Product
    Expression System
    Conjugate
    Origin
    Price starts at
    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Mouse
    Price starts at $16,231.82
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Mouse
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    FAP (Fibroblast Activation Protein, alpha (FAP))

    Alternative Name

    FAP

    Background

    This gene belongs to the serine protease family. The encoded protein is an inducible cell-surface bound glycoprotein specifically expressed in tumor-associated fibroblasts and pericytes of epithelial tumors and has protease and gelatinase activity. The protein plays a role in remodeling of the extracellular matrix (ECM) and may affect tumorigenesis and tissue repair. Alternately spliced transcript variants of this gene are described in the literature (PMID 9139873), but the full-length sequence of these variants is not available.

    Molecular Weight

    predicted molecular mass of 111.4 kDa after removal of the signal peptide.The apparent molecular mass of Mouse-FAP-mFc is 130 kDa due to glycosylation.

    Gene ID

    14089

    UniProt

    P97321

    Pathways

    Tube Formation
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