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Claudin 3 Protein (CLDN3) (Fc Tag)

CLDN3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6964182
  • Target See all Claudin 3 (CLDN3) Proteins
    Claudin 3 (CLDN3)
    Protein Type
    Recombinant
    Origin
    • 7
    • 3
    • 2
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Claudin 3 protein is labelled with Fc Tag.
    Purpose
    Recombinant human CLDN3 protein with C-terminal human Fc tag
    Specificity
    CLDN3 (Arg30-Arg80) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CLDN3 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Claudin 3 (CLDN3)
    Alternative Name
    CLDN3 (CLDN3 Products)
    Synonyms
    claudin-3 Protein, cpe-r2 Protein, cpetr2 Protein, hrvp1 Protein, rvp1 Protein, CLDN3 Protein, LOC100228090 Protein, C7orf1 Protein, CPE-R2 Protein, CPETR2 Protein, HRVP1 Protein, RVP1 Protein, AI182374 Protein, Cpetr2 Protein, mRVP1 Protein, claudin 3 L homeolog Protein, claudin 3 Protein, claudin-4-like Protein, cldn3.L Protein, cldn3 Protein, CLDN3 Protein, LOC100228090 Protein, Cldn3 Protein
    Background
    Synonymes: C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
    Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
    Molecular Weight
    predicted molecular mass of 31.8 kDa after removal of the signal peptide. The apparent molecular mass of CLDN3-hFc is 35-40 kDa due to glycosylation.
    UniProt
    O15551
    Pathways
    Hepatitis C
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