Claudin 3 Protein (CLDN3) (Fc Tag)
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- Target See all Claudin 3 (CLDN3) Proteins
- Claudin 3 (CLDN3)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Claudin 3 protein is labelled with Fc Tag.
- Purpose
- Recombinant human CLDN3 protein with C-terminal human Fc tag
- Specificity
- CLDN3 (Arg30-Arg80) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CLDN3 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Claudin 3 (CLDN3)
- Alternative Name
- CLDN3 (CLDN3 Products)
- Synonyms
- claudin-3 Protein, cpe-r2 Protein, cpetr2 Protein, hrvp1 Protein, rvp1 Protein, CLDN3 Protein, LOC100228090 Protein, C7orf1 Protein, CPE-R2 Protein, CPETR2 Protein, HRVP1 Protein, RVP1 Protein, AI182374 Protein, Cpetr2 Protein, mRVP1 Protein, claudin 3 L homeolog Protein, claudin 3 Protein, claudin-4-like Protein, cldn3.L Protein, cldn3 Protein, CLDN3 Protein, LOC100228090 Protein, Cldn3 Protein
- Background
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Synonymes: C7orf1, CPE-R2, CPETR2, HRVP1, RVP1
Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. - Molecular Weight
- predicted molecular mass of 31.8 kDa after removal of the signal peptide. The apparent molecular mass of CLDN3-hFc is 35-40 kDa due to glycosylation.
- UniProt
- O15551
- Pathways
- Hepatitis C
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