TLR3 Protein (Fc Tag)
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- Target See all TLR3 Proteins
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TLR3 protein is labelled with Fc Tag.
- Purpose
- Recombinant human TLR3 protein with C-terminal human Fc tag
- Specificity
- TLR3 (Glu28-Pro80) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TLR3 Protein
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Toll-Like Receptor 3 (TLR3) (AA 23-703) protein (His tag)
TLR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Toll-Like Receptor 3 (TLR3) (AA 25-705) protein (His tag)TLR3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Toll-Like Receptor 3 (TLR3) (AA 31-711) protein (His tag)TLR3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Toll-Like Receptor 3 (TLR3) (AA 601-700) protein (GST tag)TLR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Toll-Like Receptor 3 (TLR3) (AA 23-703) protein (His tag,Biotin)TLR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Toll-Like Receptor 3 (TLR3) (AA 726-904) protein (His tag)Crystallography grade TLR3 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Toll-Like Receptor 3 (TLR3) (AA 727-905) protein (His tag)Crystallography grade TLR3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Toll-Like Receptor 3 (TLR3) (AA 24-704) protein (His tag)Crystallography grade TLR3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Toll-Like Receptor 3 (TLR3) (AA 26-705) protein (His tag)Crystallography grade TLR3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Toll-Like Receptor 3 (TLR3) (AA 24-904) protein (rho-1D4 tag)Crystallography grade TLR3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Alternative Name
- TLR3 (TLR3 Products)
- Synonyms
- CD283 Protein, IIAE2 Protein, AI957183 Protein, zgc:123006 Protein, toll like receptor 3 Protein, toll-like receptor 3 Protein, TLR3 Protein, Tlr3 Protein, tlr3 Protein
- Background
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Synonymes: CD283, IIAE2
Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008] - Molecular Weight
- predicted molecular mass of 103.5 kDa after removal of the signal peptide. The apparent molecular mass of TLR3-hFc is 130-180 kDa due to glycosylation.
- UniProt
- O15455
- Pathways
- TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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