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DKK2 Protein (Fc Tag)

DKK2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6964354
  • Target See all DKK2 Proteins
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Protein Type
    Recombinant
    Origin
    • 9
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DKK2 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human DKK2 with C-terminal human Fc tag
    Specificity
    DKK2 (Lys34-Ile259) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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    Discover our top product DKK2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Alternative Name
    DKK2 (DKK2 Products)
    Synonyms
    DKK-2 Protein, Dkk4 Protein, zgc:171574 Protein, dickkopf WNT signaling pathway inhibitor 2 Protein, DKK2 Protein, Dkk2 Protein, dkk2 Protein
    Background
    Synonymes: DKK-2
    Description: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 51.2 kDa after removal of the signal peptide. The apparent molecular mass of DKK2-hFc is 55-70 kDa due to glycosylation.
    UniProt
    Q9UBU2
    Pathways
    WNT Signaling
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