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SARS-CoV-2 Spike S1 Protein (B.1.351 - beta) (Fc Tag)

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN6992404
  • Target See all SARS-CoV-2 Spike S1 Proteins
    SARS-CoV-2 Spike S1
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    B.1.351 - beta
    Origin
    • 94
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
    Source
    • 86
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SARS-CoV-2 Spike S1 protein is labelled with Fc Tag.
    Purpose
    SARS-CoV-2 S1 protein (L18F, D80A, D215G, LAL242-244del, R246I, K417N, E484K, N501Y, D614G), Fc Tag
    Sequence
    AA 16-685
    Characteristics
    SARS-CoV-2 S1 protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). The mutations (L18F, D80A, D215G, LAL242-244del, R246I, K417N, E484K, N501Y, D614G) were identified in the SARS-CoV-2 variant (known as B.1.351 or 20C/501Y.V2) which emerged in the South Africa.
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SARS-CoV-2 Spike S1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    Storage
    -20 °C
  • Target
    SARS-CoV-2 Spike S1
    Alternative Name
    SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 Products)
    Target Type
    Viral Protein
    Background
    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    Molecular Weight
    101.1 kDa
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