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SARS-CoV-2 Spike Protein (B.1.617.1 - kappa, RBD) (Fc Tag)

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Catalog No. ABIN7013117
  • Target See all SARS-CoV-2 Spike Proteins
    SARS-CoV-2 Spike
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    B.1.617.1 - kappa, RBD
    Origin
    • 223
    • 37
    • 9
    • 7
    • 7
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    • 6
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    • 3
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    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Kappa
    Source
    • 198
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SARS-CoV-2 Spike protein is labelled with Fc Tag.
    Purpose
    SARS-CoV-2 Spike RBD (L452R, E484Q), Fc Tag (MALS verified)
    Specificity
    SARS-CoV-2 Spike RBD (L452R, E484Q)
    Characteristics
    SARS-CoV-2 Spike RBD (L452R, E484Q), Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1(L452R, E484Q). The mutations (L452R, E484Q) were identified in the SARS-CoV-2 variants which emerged in India (known as B.1.617).
    Purity
    >95 % as determined by reduced SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SARS-CoV-2 Spike Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    Storage
    -20 °C
  • Target
    SARS-CoV-2 Spike
    Abstract
    SARS-CoV-2 Spike Products
    Target Type
    Viral Protein
    Background
    It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    Molecular Weight
    51.1 kDa
    NCBI Accession
    QHD43416
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