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Complement C2 Protein (AA 21-752) (His tag)

Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7013389
  • Target See all Complement C2 Proteins
    Complement C2
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-752
    Origin
    • 9
    • 3
    • 2
    • 1
    Human
    Source
    • 6
    • 5
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Complement C2 protein is labelled with His tag.
    Characteristics
    Human Complement Component C2 Protein, His Tag (MALS verified) (active enzyme)
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product Complement C2 Protein
  • Application Notes
    MALS verified
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    20 mM Tris, 150 mM NaCl, pH 7.5
    Storage
    -20 °C
  • Target
    Complement C2
    Alternative Name
    Complement Component C2 (Complement C2 Products)
    Synonyms
    CO2 Protein, complement C2 Protein, complement component 2 (within H-2S) Protein, C2 Protein
    Background
    C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.
    Molecular Weight
    83.0 kDa
    NCBI Accession
    NP_000054
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