Complement C2 Protein (AA 21-752) (His tag)
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- Target See all Complement C2 Proteins
- Complement C2
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-752
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Complement C2 protein is labelled with His tag.
- Characteristics
- Human Complement Component C2 Protein, His Tag (MALS verified) (active enzyme)
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product Complement C2 Protein
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- Application Notes
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 20 mM Tris, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- Complement C2
- Alternative Name
- Complement Component C2 (Complement C2 Products)
- Synonyms
- CO2 Protein, complement C2 Protein, complement component 2 (within H-2S) Protein, C2 Protein
- Background
- C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.
- Molecular Weight
- 83.0 kDa
- NCBI Accession
- NP_000054
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