FAP Protein (AA 26-760) (Fc Tag)
Quick Overview for FAP Protein (AA 26-760) (Fc Tag) (ABIN7013469)
Target
See all FAP ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 26-760
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Purification tag / Conjugate
- This FAP protein is labelled with Fc Tag.
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Characteristics
- Human FAP Protein, Fc Tag (active enzyme)
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (Fc Tag)
FAP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (His-Avi Tag,Biotin)FAP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-761) protein (His tag)FAP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (His tag)FAP Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (His-Avi Tag,Biotin)FAP Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 1-760) protein (His tag)custom-made FAP Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fibroblast Activation Protein, alpha (FAP) (AA 1-761) protein (His tag)custom-made FAP Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fibroblast Activation Protein, alpha (FAP) (AA 30-760) protein (His tag)FAP Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) (Active) protein (His tag)FAP Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Fibroblast Activation Protein, alpha (FAP) (AA 525-624) protein (GST tag)FAP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- FAP (Fibroblast Activation Protein, alpha (FAP))
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Alternative Name
- FAP
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Background
- FAP (also known as seprase) is a Type II transmembrane serine protease. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences. Degrade also gelatin, heat-denatured type I collagen. Also has dipeptidyl peptidase activity, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner.
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Molecular Weight
- 111.5 kDa
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Pathways
- Tube Formation
Target
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