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MUC17 Protein (AA 4131-4390) (His tag)

MUC17 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7013506
  • Target See all MUC17 products
    MUC17 (Mucin 17, Cell Surface Associated (MUC17))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 4131-4390
    Origin
    Human
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This MUC17 protein is labelled with His tag.
    Characteristics
    Human MUC-17 Protein, His Tag
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    MUC17 (Mucin 17, Cell Surface Associated (MUC17))
    Alternative Name
    MUC-17 (MUC17 Products)
    Synonyms
    MUC3 Protein, mucin 17, cell surface associated Protein, MUC17 Protein
    Background
    Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
    Molecular Weight
    31.2 kDa
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