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RNF43 Protein (AA 44-197) (Fc Tag)

RNF43 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN7013543
  • Target See all RNF43 Proteins
    RNF43 (Ring Finger Protein 43 (RNF43))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 44-197
    Origin
    • 6
    • 3
    Human
    Source
    • 4
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This RNF43 protein is labelled with Fc Tag.
    Characteristics
    Human RNF43 Protein, Fc Tag (MALS verified)
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    RNF43 (Ring Finger Protein 43 (RNF43))
    Alternative Name
    RNF43 (RNF43 Products)
    Synonyms
    RNF124 Protein, URCC Protein, 4732452J19Rik Protein, RGD1305204 Protein, ring finger protein 43 Protein, RNF43 Protein, Rnf43 Protein
    Background
    E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)
    Molecular Weight
    43.5 kDa
    Pathways
    WNT Signaling
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