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STEAP1 Protein (AA 2-339) (His tag)

STEAP1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7013747
$3,161.54
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  • Target See all STEAP1 Proteins
    STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 2-339
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This STEAP1 protein is labelled with His tag.
    Purpose
    Human STEAP1 Full Length Protein, His Tag (HEK293)
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5
    Storage
    -80 °C
  • Target
    STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
    Alternative Name
    STEAP1 (STEAP1 Products)
    Synonyms
    PRSS24 Protein, STEAP Protein, STEAP1 Protein, 2410007B19Rik Protein, Prss24 Protein, Steap Protein, STEAP family member 1 Protein, six transmembrane epithelial antigen of the prostate 1 Protein, STEAP1 Protein, Steap1 Protein
    Background
    Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
    Molecular Weight
    41.7 kDa
    NCBI Accession
    NP_036581
    Pathways
    Transition Metal Ion Homeostasis
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