SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (BA.2 - Omicron) (His tag)

Catalog No. ABIN7072155

Product Details

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Protein Type: Recombinant

Protein Characteristics: BA.2 - Omicron

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

Source: HEK-293 Cells

Purification tag / Conjugate: This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purpose: SARS-CoV-2 Nucleocapsid protein, His Tag (BA.2/Omicron)

Characteristics: SARS-CoV-2 Nucleocapsid protein, His Tag (BA.2/Omicron) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (P13L, ERS31-33del, R203K, G204R, S413R). The nucleocapsid mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2; GISAID clade: GRA; Nextstrain clade: 21L). This protein carries a polyhistidine tag at the C-terminus.

Sterility: 0.22 μm filtered

Application Details

Comment:

The protein has a calculated MW of 47.1 kDa.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C/-80 °C

Storage Comment: For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 months under sterile conditions after reconstitution.

Expiry Date: 12 monts

Target Details

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Alternative Name: SARS-CoV-2 N protein (SARS-CoV-2 N Products)

Synonyms: nucleocapsid phosphoprotein Protein, N Protein

Target Type: Viral Protein

Background: Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Molecular Weight: 47.1 kDa