FAP Protein (AA 30-760) (His tag)

Catalog No. ABIN7092782

This Recombinant FAP protein is expressed in HEK-293 Cells.

Quick Overview for FAP Protein (AA 30-760) (His tag) (ABIN7092782)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 30-760

Purification tag / Conjugate: This FAP protein is labelled with His tag.

Purpose: Recombinant human FAP(30-760) protein with N-terminal 6xHis tag

Specificity: 6xHis tag FAP (30-760) (Arg30-Asp760)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Alternative Name: FAP

Background: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: predicted molecular mass of 85.4 kDa after removal of the signal peptide. The apparent molecular mass of His-FAP(30-760) is 100-130 kDa due to glycosylation.

UniProt: Q12884

Pathways: Tube Formation