K-RAS Protein (His tag)

Catalog No. ABIN7092804

Product Details

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This K-RAS protein is labelled with His tag.

Purpose: Recombinant human KRAS protein with C-terminal 6xHis tag

Specificity: KRAS (Thr2-Cys185) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Alternative Name: KRAS (KRAS Products)

Synonyms: wu:fa04e08 Protein, wu:fc14b12 Protein, wu:fc23g10 Protein, wu:fj89d12 Protein, zgc:85725 Protein, Kras2 Protein, c-Ki-ras Protein, p21 Protein, C-K-RAS Protein, CFC2 Protein, K-RAS2A Protein, K-RAS2B Protein, K-RAS4A Protein, K-RAS4B Protein, KI-RAS Protein, KRAS1 Protein, KRAS2 Protein, NS Protein, NS3 Protein, RASK2 Protein, AI929937 Protein, K-ras Protein, Ki-ras Protein, Kras-2 Protein, p21B Protein, ras Protein, k-ras Protein, kras Protein, kras-a Protein, kras-b Protein, rask2 Protein, K-RAS Protein, p21ras Protein, KRAS proto-oncogene, GTPase Protein, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog Protein, Kirsten rat sarcoma viral oncogene homolog Protein, semicolonial-7 Protein, Ras family protein Protein, GTPase KRas Protein, Kirsten rat sarcoma viral oncogene homolog S homeolog Protein, KRAS Protein, kras Protein, Kras Protein, smco-7 Protein, PGTG_03066 Protein, Tsp_02666 Protein, Tsp_01642 Protein, rask Protein, kras.S Protein

Target Type: Viral Protein

Background: Synonymes: C-K-RAS
Description: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 21.8 kDa after removal of the signal peptide. The apparent molecular mass of KRAS-His is 15-25 kDa due to glycosylation.

UniProt: P01116