R-Spondin 3 Protein (RSPO3) (Fc Tag)
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- Target See all R-Spondin 3 (RSPO3) Proteins
- R-Spondin 3 (RSPO3)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This R-Spondin 3 protein is labelled with Fc Tag.
- Purpose
- Recombinant human RSPO3(22-146) protein with C-terminal human Fc tag
- Specificity
- RSPO3 (22-146) (Ser19-Glu351) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product RSPO3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- R-Spondin 3 (RSPO3)
- Alternative Name
- RSPO3 (RSPO3 Products)
- Synonyms
- pwtsr Protein, thsd2 Protein, cristin1 Protein, CRISTIN1 Protein, PWTSR Protein, THSD2 Protein, RGD1563246 Protein, 2810459H04Rik Protein, AW742308 Protein, Cristin1 Protein, Thsd2 Protein, R-spondin 3 Protein, rspo3 Protein, RSPO3 Protein, Rspo3 Protein
- Background
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Synonymes: CRISTIN1
Description: This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013] - Molecular Weight
- predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO3(22-146)-hFc is 35-55 kDa due to glycosylation.
- UniProt
- Q9BXY4
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