hCoV-OC43 Spike Protein (His tag)

Catalog No. ABIN7121349

Product Details

Target: hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))

Protein Type: Recombinant

Origin: Human Coronavirus OC43 (HCoV-OC43)

Source: Insect Cells

Purification tag / Conjugate: This hCoV-OC43 Spike protein is labelled with His tag.

Purpose: HCoV-OC43 Spike protein, His Tag

Sequence: Ala 14 - Pro 1297 (RRSRG 754-758 GGSGG)

Specificity: HCoV-OC43 Spike protein

Characteristics: HCoV-OC43 Spike protein, His Tag (SPN-H52Hz) is expressed from Baculovirus-Insect cells. It contains AA Ala 14 - Pro 1297 (RRSRG 754-758 GGSGG) (Accession # P36334-1).

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 148.3 kDa. The protein migrates as 150 kDa under reducing (R) condition .

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))

Alternative Name: HCoV-OC43 Spike protein (HCoV-OC43 S Products)

Background: Synonyms: Spike,S protein,Spike glycoprotein,S glycoprotein,
Description: Human coronavirus OC43 (HCoV-OC43) is one of seven known coronaviruses to infect humans, which is responsible for the common cold and may have been responsible for the 1889-1890 pandemic. The infecting coronavirus is an enveloped, positive-sense, single-stranded RNA virus that enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor. The spike protein of HCoV-OC43 is a trimer protruding from the viral membrane to engage cellular receptors and mediate viral fusion with host membranes. Each spike trimer contains two large regions: N-terminal S1 responsible for receptor binding and C-terminal S2 responsible for fusion.

Molecular Weight: 148.3 kDa