ECM1 Protein (His tag)
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- Target See all ECM1 Proteins
- ECM1 (Extracellular Matrix Protein 1 (ECM1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ECM1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse ECM1 Protein (His Tag)(Active)
- Sequence
- Met 1-Glu 559
- Characteristics
- A DNA sequence encoding the mouse ECM1 isoform 1 (Q61508-1) (Met 1-Glu 559) was expressed, fused with a polyhistidine tag at the C-terminus.
- Purity
- > 88 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to bind human MMP-9 in a functional ELISA.
- Top Product
- Discover our top product ECM1 Protein
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Extracellular Matrix Protein 1 (ECM1) (AA 24-210) protein (His-IF2DI Tag)
ECM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Extracellular Matrix Protein 1 (ECM1) (AA 1-540) protein (GST tag)ECM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Extracellular Matrix Protein 1 (ECM1) (AA 20-540) protein (His tag)Crystallography grade ECM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Extracellular Matrix Protein 1 (ECM1) (AA 20-559) protein (His tag)Crystallography grade ECM1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Extracellular Matrix Protein 1 (ECM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ECM1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ECM1 (Extracellular Matrix Protein 1 (ECM1))
- Alternative Name
- ECM1 (ECM1 Products)
- Synonyms
- URBWD Protein, ECM Protein, EMILIN4 Protein, GPIa* Protein, MMRN Protein, AI663821 Protein, p85 Protein, extracellular matrix protein 1 Protein, multimerin 1 Protein, ECM1 Protein, MMRN1 Protein, Ecm1 Protein
- Background
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Background: Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling.
Synonym: AI663821;p85
- Molecular Weight
- 62.5 kDa
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