NELL2 Protein (His tag)
Quick Overview for NELL2 Protein (His tag) (ABIN7317297)
Target
See all NELL2 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This NELL2 protein is labelled with His tag.
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Purpose
- Recombinant Human NELL2 Protein (His Tag)
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Sequence
- Met 1-Leu 816
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Characteristics
- A DNA sequence encoding the human NELL2 (Q99435) (Met 1-Leu 816) was fused with a polyhistidine tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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NEL-Like 2 (Chicken) (NELL2) (AA 1-816) protein (GST tag)
NELL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NEL-Like 2 (Chicken) (NELL2) (AA 22-238) protein (His tag)NELL2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant ~95 % WB, ELISA, MS, Neut
NEL-Like 2 (Chicken) (NELL2) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)NELL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- NELL2 (NEL-Like 2 (Chicken) (NELL2))
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Alternative Name
- NELL2
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Background
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Background: OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.Immune CheckpointImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: NRP2
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Molecular Weight
- 90.4 kDa
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UniProt
- Q99435
Target
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