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SECTM1A Protein (His tag)

SECTM1A Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7320896
  • Target See all SECTM1A products
    SECTM1A (Secreted and Transmembrane 1A (SECTM1A))
    Protein Type
    Recombinant
    Origin
    Mouse
    Source
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This SECTM1A protein is labelled with His tag.
    Purpose
    Recombinant Mouse SECTM1A (C-6His)
    Sequence
    Gln28-Thr165
    Characteristics
    Recombinant Mouse Secreted And Transmembrane Protein 1A is produced by our Mammalian expression system and the target gene encoding Gln28-Thr165 is expressed with a 6His tag at the C-terminus.
    Purity
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SECTM1A (Secreted and Transmembrane 1A (SECTM1A))
    Alternative Name
    SECTM1A (SECTM1A Products)
    Synonyms
    BC010462 Protein, secreted and transmembrane 1A Protein, Sectm1a Protein
    Background

    Background: SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect human SECTM1 expression, and it is thought to be an interferon early response gene. Mouse SECTM1A cDNA encodes a signal sequence, an extracellular domain with four potential N linked glycosylation sites, a transmembrane sequence, and a very short (approximately 6 aa) cytoplasmic sequence. SECTM1 proteins from human and mouse show species specific binding of CD7 and co stimulation of T cells, including enhancement of CD3 induced proliferation.

    Synonym: SECTM1A, Sectm1a

    Molecular Weight
    16.2 kDa
    UniProt
    A2ABP9
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