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C6 Protein (His tag)

C6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7198986
  • Target See all C6 Proteins
    C6 (Complement Component 6 (C6))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This C6 protein is labelled with His tag.
    Purpose
    Recombinant Human C6/complement component 6 Protein (His Tag)
    Sequence
    Met 1-Ala 934
    Characteristics
    A DNA sequence encoding the human C6 (AAA59668.1) (Met 1-Ala 934) was fused with a polyhistidine tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
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    Discover our top product C6 Protein
  • Comment

    110 kDa

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    C6 (Complement Component 6 (C6))
    Alternative Name
    complement component 6 (C6 Products)
    Synonyms
    zgc:64073 Protein, MGC82168 Protein, c6 Protein, MGC89471 Protein, C6 Protein, AW111623 Protein, complement component 6 Protein, complement C6 Protein, complement component 6, gene 1 L homeolog Protein, complement component 6, gene 2 Protein, c6 Protein, C6 Protein, c6.1.L Protein, c6.2 Protein
    Background

    Background: Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46 and GAP43, is a cell membrane protein which belongs to the neuromodulin family. Neuromodulin / GAP43 contains one IQ domain. Neuromodulin / GAP43 is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Neuromodulin / GAP43 is involved in neurite outgrowth, a crucial process for the differentiation of neurons. The sudden infant death syndrome (SIDS) is the main cause of postneonatal infant death and its cause is still unknown. Neuromodulin / GAP43 is a marker of synaptic plasticity and is critical for normal development of the serotonergic innervation. Neuromodulin / GAP43 is a major cortical cytoskeleton-associated and calmodulin binding protein that is widely and abundantly expressed during development, maintained in selected brain structures in the adult, and reinduced during nerve regeneration. CAP23 and GAP43 are functionally related intrinsic determinants of anatomical plasticity. These proteins function by locally promoting subplasmalemmal actin cytoskeleton accumulation.

    Synonym: C6

    Molecular Weight
    104 kDa
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